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A potential anti-coagulant role of complement factor H

Janez Ferluga1, Uday Kishore2, Robert B Sim3

  • 1Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK; Centre for Infection, Immunity and Disease Mechanisms, Biosciences, Heinz Wolff Building, Brunel University, London UB8 3PH, UK.

Molecular Immunology
|March 18, 2014
PubMed
Summary

Complement factor H (FH) exhibits previously unknown anti-thrombotic properties, inhibiting blood coagulation pathways. This finding offers new insights into anti-phospholipid syndrome (APS) and potential therapeutic targets.

Keywords:
Factor Hanti-phospholipid syndromecoagulationcomplement

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