Severe enteropathy caused by α-heavy chain disease lacking detectable M-proteins

Miwa Kurimoto1, Takashi Sonoki, Yasushi Nakamura

  • 1Department of Hematology/Oncology, Wakayama Medical University, Japan.

Summary

Alpha-heavy chain disease (α-HCD) diagnosis can be challenging when M-proteins are undetectable. Immunohistochemistry on intestinal biopsies is crucial for confirming α-HCD in such cases.

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