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The intranasal Schirmer test: a preliminary study to quantify nasal secretion
Joerg Lindemann1, Evangelia Tsakiropoulou, Gerhard Rettinger
1Department of Otorhinolaryngology, University of Ulm, Frauensteige 12, 89075, Ulm, Germany.
Summary
A new intranasal Schirmer test effectively measures nasal secretion, establishing normal values for healthy individuals. Smokers showed significantly reduced nasal secretion compared to non-smokers.
Area of Science:
- Otorhinolaryngology
- Nasal Physiology
- Diagnostic Testing
Background:
- Adequate nasal mucosal secretion is vital for normal nasal function.
- A dry nose is a common patient complaint in ENT clinics.
- Current methods for measuring nasal secretion are lacking.
Purpose of the Study:
- To assess the feasibility of an intranasal Schirmer test for quantifying nasal secretion.
- To establish standard values for nasal secretion in healthy individuals.
- To compare nasal secretion in smokers versus non-smokers.
Main Methods:
- An intranasal Schirmer test was performed on 159 non-smokers and 30 smokers.
- Test strips were placed on the anterior nasal septum for 10 minutes.
- Wetted distance was measured; nasal endoscopy, rhinomanometry, and acoustic rhinometry were also conducted.
Main Results:
- The median wetted distance in non-smokers was 10.3 mm (range 3.6-35.0 mm).
- Smokers had a significantly shorter median wetted distance of 8.4 mm (p < 0.05).
- Age, gender, nasal geometry, and airflow did not significantly impact secretion.
Conclusions:
- The intranasal Schirmer test is a practical, inexpensive, and well-tolerated method for measuring nasal mucosal humidification.
- Normal wetting distances for healthy individuals range from 6 to 18 mm.
- Smoking is associated with reduced nasal secretion.
