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Related Experiment Videos

Implantable defibrillation: eight years clinical experience.

A C Thomas1, S A Moser, M L Smutka

  • 1Department of Scientific Studies, Cardiac Pacemakers, Inc., St. Paul, MN 55112-5798.

Pacing and Clinical Electrophysiology : PACE
|November 1, 1988
PubMed
Summary

The automatic implantable cardioverter defibrillator (AICD) significantly improved survival rates for patients with ventricular tachycardia/fibrillation. This device reduced sudden cardiac death, demonstrating its crucial role in cardiac patient care.

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Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Medical Devices

Background:

  • The automatic implantable cardioverter defibrillator (AICD) was developed to treat life-threatening cardiac arrhythmias.
  • Early AICD implantation began in 1980, with cardioversion capabilities added in 1982.

Purpose of the Study:

  • To evaluate the survival impact and device performance of the AICD in a large patient cohort.
  • To assess the incidence of sudden cardiac death (SCD) and device-related complications.

Main Methods:

  • Analysis of data from 3610 patients implanted with AICD pulse generators between April 1982 and April 1988.
  • Inclusion criteria: recurrent ventricular tachycardia and/or fibrillation.
  • Follow-up averaged 12.2 months, with survival and device performance data collected.

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Main Results:

  • Cumulative survival from SCD was high, reaching 93.7% at 48 months.
  • Operative mortality was 2.5%, with complications similar to pacemakers.
  • AICD pulse generator survival was 86.4% at 30 months, with 33% of patients experiencing spontaneous countershocks.

Conclusions:

  • The AICD has demonstrated a significant positive impact on patient survival, particularly in preventing sudden cardiac death.
  • The device shows acceptable operative mortality and complication rates comparable to existing pacemakers.
  • Long-term device survival is robust, supporting its efficacy in managing high-risk cardiac patients.