[Dynamic thyroid hormone levels during the thyrostatic treatment of Basedow's disease]

The thyroid hormones and thyrotropic hormone levels were followed up dynamically in the course of thyrostatic treatment in 24 newly discovered patients with Basedow's disease. The following findings deserve special attention: 1. The early appearance of therapeutic remission--mean after 2.4 months of treatment, 2. The increase of the thyrotropic hormone following soon after remission is achieved--mean at the end of the forth month of treatment it reaches 19.5 mIU. The analysis revealed that this high mean level was due to 9 patients who had reacted with initial hypothyroidism though they were under the same therapeutic conditions. The data allow the conclusion that there are individual differences in thyroid suppressibility. This implies a dynamic follow up of the thyrostatic hormonal action and timely correction of the dose which would remove the consequences of improper dosage.