Effects of botulinum toxin type A for spastic foot in post-stroke patients enrolled in a rehabilitation program
Leonardo Halley Carvalho Pimentel1, Francisco José Alencar1, Leonardo Raphael Santos Rodrigues1
1Centro Integrado de Reabilitação, TeresinaPI, Brazil.
Unlabelled:
The objective of this study was to evaluate the effects of botulinum toxin type A (BTX-A) on spastic foot in stroke patients in a rehabilitation program.
Method:
Hemiparetic stroke patients (n=21) enrolled in a rehabilitation program were divided into two groups. The first group (n=11) received a total of 300 UI BTX-A, and the second group (n=10) received 100 UI BTX-A. All patients were assessed at baseline and 2, 4, 8 and 12 weeks after injection for Modified Ashworth Score, time walking 10 meters, and the Functional Independence Measure (mFIM) motor score.
Results:
The higher-dose group exhibited a significant improvement in spasticity, and both groups showed an improvement in time walking 10 meters and mFIM, with no significant differences between them.
Conclusions:
Our findings suggest that gains in gait velocity and functional independence were not correlated to BTX-A dose.
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