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Childhood overweight or obesity increases the risk of IIH recurrence fivefold

H Stiebel-Kalish1, I Serov2, R Sella2

  • 11] Department of Ophthalmology, Rabin Medical Center, Petah Tikva, Israel [2] Neuro-Ophthalmology Unit, Department of Ophthalmology, Rabin Medical Center, Petah Tikva, Israel [3] Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

International Journal of Obesity (2005)
|March 19, 2014
PubMed

Insights

Children who are overweight or obese have a fivefold higher risk of idiopathic intracranial hypertension (IIH) recurrence. Weight management may reduce the risk of IIH recurrence in children.

Area of Science:

  • Pediatrics
  • Neurology
  • Public Health

Background:

  • Idiopathic intracranial hypertension (IIH) is a neurological condition affecting children.
  • The association between overweight/obesity and IIH recurrence in pediatric populations requires further investigation.

Purpose of the Study:

  • To investigate whether being overweight or obese is a risk factor for IIH recurrence in children.
  • To compare the risk of IIH recurrence between healthy-weight children and those who are overweight or obese.

Main Methods:

  • Retrospective case-control series involving 43 children with IIH.
  • Follow-up averaged 9 ± 3.4 years.
  • Survival curve analysis (log-rank test) was used to compare recurrence rates based on body mass index (BMI) percentile.

Main Results:

  • The overall risk for long-term IIH recurrence in children was approximately 20%.
  • Children with a BMI ⩾ 85th percentile had a fivefold higher risk of IIH recurrence (57%) compared to healthy-weight children (11%).
  • The difference in recurrence risk was statistically significant (P = 0.04).

Conclusions:

  • Overweight and obesity are significant risk factors for IIH recurrence in children.
  • Weight control counseling for families may help decrease the risk of IIH recurrence.
  • Pediatricians should consider BMI when assessing IIH recurrence risk in children.

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