Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

7.6K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
7.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Factors influencing diagnostic yield and complication risk in computed tomography fluoroscopy-guided lung biopsies: a 10-year single-center study.

Diagnostic and interventional radiology (Ankara, Turkey)·2025
Same author

Quantitative differentiation of minimal-fat angiomyolipomas from renal cell carcinomas using grating-based x-ray phase-contrast computed tomography: An ex vivo study.

PloS one·2023
Same author

REDUCE - Indication catalogue based ordering of chest radiographs in intensive care units.

Journal of critical care·2022
Same author

[Future perspectives: how does artificial intelligence influence the development of our profession?]

Der Radiologe·2022
Same author

[Structured reporting: why and why not now?]

Der Radiologe·2021
Same author

[Personalised medicine and interdisciplinarity : A reality in the diagnosis and treatment of primary prostate carcinoma].

Der Radiologe·2021

Related Experiment Video

Updated: May 2, 2026

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
09:30

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

18.6K

Flip angle-optimized fast dynamic T1 mapping with a 3D gradient echo sequence.

Olaf Dietrich1, Maximilian Freiermuth, Linus Willerding

  • 1Josef Lissner Laboratory for Biomedical Imaging, Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital Munich, Germany.

Magnetic Resonance in Medicine
|March 19, 2014
PubMed
Summary
This summary is machine-generated.

This study optimizes a fast 3D T1 mapping technique using a single flip angle (1FA) approach. The flip angle-optimized 1FA method enhances the statistical precision of T1 measurements in dynamic imaging.

Keywords:
contrast agent concentrationfast dynamic imaginglongitudinal relaxation time T1magnetic resonance imaging

More Related Videos

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
15:48

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

Published on: December 15, 2014

25.0K
Assessment of Cardiac Function and Myocardial Morphology Using Small Animal Look-locker Inversion Recovery SALLI MRI in Rats
08:41

Assessment of Cardiac Function and Myocardial Morphology Using Small Animal Look-locker Inversion Recovery SALLI MRI in Rats

Published on: July 19, 2013

12.0K

Related Experiment Videos

Last Updated: May 2, 2026

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
09:30

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

18.6K
Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
15:48

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

Published on: December 15, 2014

25.0K
Assessment of Cardiac Function and Myocardial Morphology Using Small Animal Look-locker Inversion Recovery SALLI MRI in Rats
08:41

Assessment of Cardiac Function and Myocardial Morphology Using Small Animal Look-locker Inversion Recovery SALLI MRI in Rats

Published on: July 19, 2013

12.0K

Area of Science:

  • Magnetic Resonance Imaging
  • Quantitative MRI

Background:

  • Accurate T1 mapping is crucial for various MRI applications.
  • Fast 3D T1 mapping techniques are needed for dynamic studies.
  • Variable Flip Angle (VFA) methods offer speed but require optimization.

Purpose of the Study:

  • To analyze flip angle dependence in VFA-based 3D T1 mapping.
  • To optimize statistical precision for a fast 3D T1 mapping technique.
  • To validate a single flip angle (1FA) approach for dynamic T1 series.

Main Methods:

  • Calculated optimal flip angle (αdyn,opt) by minimizing statistical error of T1.
  • Acquired single 3D spoiled gradient echo data sets for dynamic series.
  • Measured T1 maps using saturation recovery (SR) and VFA/1FA with 11 flip angles in phantoms.

Main Results:

  • Measured statistical error of 1FA technique matched theoretical predictions.
  • Optimal flip angle varied from 5° (T1=2629 ms) to 30° (T1=137 ms).
  • Relative deviation between 1FA and SR measurements ranged from -2.9% to +10.3%.

Conclusions:

  • The flip angle-optimized 1FA technique improves T1 value precision in dynamic phantom measurements.
  • In vivo measurements validated the derived expression for the optimal flip angle.