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Pyuric diabetic patients: A tertiary centre experience from Karachi
Huma Mamun Mahmud1, Sobia Qureshi2, Darshan Kumar3
1Dr. Huma Mamun Mahmud, MBBS, MCPS (Medicine), FCPS (Nephrology), Assistant Professor, Consultant Nephrologist, Department of Medicine, Dow International Medical College, Dow University of Heath Sciences, Dow International Medical College (Ojha Campus), DUHS, Suparco Road, off Main University Road, Gulzar-e-Hijri, Scheme 33, Karachi, Pakistan.
Pakistan Journal of Medical Sciences
|March 19, 2014
Summary
Diabetic patients with pyuria frequently have urinary tract infections (UTI) or sterile pyuria. Females and those with urinary symptoms or anatomical abnormalities are more susceptible to UTI.
Area of Science:
- Urology
- Infectious Diseases
- Diabetology
Background:
- Diabetes mellitus is a common comorbidity associated with various complications.
- Pyuria, the presence of white blood cells in urine, can indicate infection or inflammation.
- Diabetic patients are at increased risk for urinary tract infections (UTIs).
Purpose of the Study:
- To determine the frequency of culture-positive urinary tract infections (UTIs) in pyuric diabetic patients.
- To ascertain the prevalence of culture-negative sterile pyuria in this population.
- To identify factors predisposing pyuric diabetic patients to UTIs.
Main Methods:
- A prospective observational study was conducted with 97 adult diabetic patients exhibiting pyuria.
- Urine culture reports were analyzed alongside clinical data.
- Data were collected using a standardized performa and analyzed using SPSS version 16.
Main Results:
- The frequency of culture-positive UTI was 60.82% (59/97) among pyuric diabetic patients.
- Culture-negative sterile pyuria was observed in 39.17% (38/97) of patients.
- UTI was more prevalent in females and associated with lower urinary tract symptoms, flank pain, stone disease, obstructed pelvicalyceal system, proteinuria, high serum creatinine, and positive nitrites.
Conclusions:
- A significant proportion of pyuric diabetic patients present with culture-positive UTI (60.82%) or sterile pyuria (39.17%).
- Factors such as female gender, symptomatic presentation, and urinary tract abnormalities are linked to increased UTI risk in this cohort.
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