Related Experiment Video

Updated: May 2, 2026

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs
08:58

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Published on: October 31, 2025

882

[Former preterm infant with bronchopulmonary dysplasia: how will this be cared for in 2014?]

A Mornand, M Roth-Kleiner, G Hafen

    Revue Medicale Suisse
    |March 20, 2014
    PubMed

    Insights

    Bronchopulmonary dysplasia is a serious complication of prematurity impacting infant lung development. This condition can lead to chronic respiratory issues persisting into adulthood.

    Area of Science:

    • Neonatal Medicine
    • Pediatric Pulmonology
    • Developmental Biology

    Context:

    • Advances in perinatal care increase survival rates for extremely premature infants.
    • Bronchopulmonary dysplasia (BPD) is a significant complication of prematurity, presenting as a developmental lung disorder.
    • The etiology of BPD is multifactorial, making prevention challenging.

    Purpose:

    • To outline the management strategies for bronchopulmonary dysplasia.
    • To emphasize the importance of supporting normal growth and reducing respiratory workload in infants with BPD.
    • To highlight the need for treatments that do not impede postnatal lung development.

    Summary:

    • Bronchopulmonary dysplasia (BPD) is a serious developmental lung disorder in premature infants.
    • Management focuses on supporting growth, easing respiratory effort, and preventing complications without hindering lung maturation.
    • BPD can manifest as bronchial hyperreactivity and obstructive patterns, leading to recurrent hospitalizations for reactive airway disease.

    Impact:

    • BPD can contribute to persistent chronic lung disease in adulthood, potentially as a novel chronic obstructive pulmonary disease (COPD) phenotype.
    • Early recognition and management are crucial for improving long-term respiratory outcomes in survivors of prematurity.
    • Understanding BPD's impact is vital for advancing pediatric respiratory medicine and long-term patient care.

    More Related Videos

    Intratracheal Instillation of Stem Cells in Term Neonatal Rats04:27

    Intratracheal Instillation of Stem Cells in Term Neonatal Rats

    Published on: May 4, 2020

    5.4K

    Related Concept Videos

    Pneumonia IV: Management01:28

    Pneumonia IV: Management

    The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
    Bacterial Pneumonia Treatment
    For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
    1.2K
    Acute Respiratory Failure-V01:29

    Acute Respiratory Failure-V

    The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
    Ensure that patients are monitored continuously for their response to therapy, including changes in...
    768
    Pneumonia V: Nursing management and Prevention01:30

    Pneumonia V: Nursing management and Prevention

    Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
    The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
    Enhance airway patency
    Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
    4.2K
    Pulmonary Cycle: Exhalation01:17

    Pulmonary Cycle: Exhalation

    In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
    5.2K
    Chronic Obstructive Pulmonary Disease-V: Nursing Management01:30

    Chronic Obstructive Pulmonary Disease-V: Nursing Management

    Nursing management of Chronic Obstructive Pulmonary Disease (COPD) is crucial for providing thorough care and support to patients. Nurses play an integral role in this process through detailed assessment, careful planning, targeted interventions, and ongoing evaluation. Here's an overview of the critical steps in nursing management for COPD.
    Assessment
    5.4K
    Flail Chest-II01:26

    Flail Chest-II

    Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
    Assessment:
    1. Clinical Evaluation:
    History:
    1.0K