Related Experiment Video
Updated: May 2, 2026

Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test OGTT and Insulin Tolerance Test ITT
Published on: January 7, 2018
Study on prevalance of diabetes mellitus in patients with T.B. under DOTS strategy
Background:
Tuberculosis is five to six times more common among diabetics than among non-diabetics and causes greater morbidity, according to reports. The effective control of each affects the control of the other. Diabetes increases the risk of developing tuberculosis, especially in developing countries with a high incidence of tuberculosis. DOTS strategy has been an effective tool on a mass basis. However, patients under DOTS are not screened for diabetes before the therapy.
Aims & Objectives:
To study the prevalence of diabetes mellitus in patients with tuberculosis under DOTS strategy.
Material & Methods:
A cross-sectional study was conducted in Santosh Medical College & Hospital, Ghaziabad, with the patients taken from different DOTS centres of NCR-Delhi, India. The present study was undertaken to evaluate the presence of undiagnosed diabetes under DOTS strategy. Fasting capillary blood glucose levels of patients diagnosed with tuberculosis were analyzed and were managed as per DOTS guidelines at multiple centres in the northwest region of India.
Results:
We studied 700 patients. The prevalence of diabetes was 12.6% (n=88), which is quite high. When category-wise analysis of diabetic subjects was done, it was found that patients under Category-I were 11.7% (n=47), patients under Cat-II were 15.5% (n=39) and those under Cat-III were 3.9% (n=2). The higher percentage of patients in Cat-II indicates the poor outcome of Cat-I patients, probably due to diabetes as a co-morbid disease.
Conclusion:
The higher prevalence of diabetes mellitus in DOTS patients raises immediate concerns in preventing the morbidity due to both the diseases. Therefore, it is recommended that some strategy on the lines of HIV disease should be formed under DOTS for the concomitant treatment of TB and diabetes for better outcome and care.
Related Concept Videos
Diabetes Mellitus: Type 2 and Gestational
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis
Type II Diabetes I: Introduction
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Carbohydrate Metabolism
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...

