[The aging particularities of bone marrow composition, pineal gland and thymus functions in mice of different lines]

We investigated the amount of stromal precursor cells for colonies of fibroblasts (CFC-F) and progenitor cells for granulocyte-macrophage colonies (CFC-GM cells), blood content of thymulin and melatonin in bone marrow of young and old mice CBA/Ca and FVB/N lines. The CBA/Ca mice demonstrated only weak increasing amount of CFC-F and CFC-GM in bone marrow, but these indices in FVB/N mice are increased more significantly. Linear difference of age-related changes in the biological features of the cells of bone marrow are significantly associated with the characteristics and relationships of the function of epiphysis and the thymus in mice of different lines during aging.