Related Experiment Video
Updated: May 2, 2026
28:13
Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
34.6K
[Especially in the hemostatic system in geriatric patients with ischemic heart disease, complicated by persistent
Advances in Gerontology = Uspekhi Gerontologii
|March 20, 2014
Insights
This study examines blood clotting and bleeding in elderly patients with coronary heart disease and persistent atrial fibrillation. Findings reveal alterations in vascular-platelet function and the coagulation-fibrinolysis system.
Area of Science:
- Cardiology
- Hematology
- Geriatrics
Background:
- Elderly individuals with coronary heart disease (CHD) often experience complications.
- Persistent atrial fibrillation (AF) is a common complication in elderly patients with CHD.
- Understanding hemostasis in this population is crucial for managing cardiovascular risk.
Purpose of the Study:
- To investigate the hemostasis system in elderly patients with CHD and persistent AF.
- To analyze the vascular-platelet, coagulation, and fibrinolysis parameters.
- To identify potential links between hemostasis and the co-occurrence of CHD and AF.
Main Methods:
- Cross-sectional study design.
- Inclusion of elderly patients diagnosed with CHD and persistent AF.
- Assessment of vascular-platelet function, coagulation factors, and fibrinolysis markers.
Main Results:
- Significant alterations were observed in the vascular-platelet system.
- Coagulation hemostasis parameters showed distinct changes.
- Fibrinolysis system activity was affected in the studied cohort.
Conclusions:
- The hemostasis system is significantly impacted in elderly patients with complicated CHD and persistent AF.
- These findings highlight the complex interplay between cardiovascular disease, arrhythmias, and blood coagulation.
- Further research is warranted to explore therapeutic implications for this patient group.
Abstract:
The article presents the results of the state of the vascular-platelet, coagulation hemostasis and fibrinolysis system in the elderly with coronary heart disease complicated with persistent atrial fibrillation.
Related Concept Videos
01:30Anticoagulant Drugs: Low-Molecular-Weight Heparins
2.6K
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
2.6K
01:24Disorders of Hemostasis
2.7K
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
2.7K
01:29Venous Thrombosis III: Interprofessional Care
482
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
482
01:30Venous Thrombosis IV: Nursing Management
415
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
415
01:17Hemorrhagic Stroke l: Introduction
20
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
20
01:00Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution
382
Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
382