Related Experiment Video

Updated: May 2, 2026

Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection
04:11

Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection

Published on: December 15, 2023

5.5K

Hepatitis B, C virus co-infection and behavioral risks in HIV-positive patients in southern Iran

Mohammad Javad Zahedi, Sodaif Darvish Moghaddam, Mehdi Hayatbakhsh Abasi

    JPMA. the Journal of the Pakistan Medical Association
    |March 20, 2014
    PubMed

    Insights

    Hepatitis C virus co-infection is common in patients with human immunodeficiency virus, with imprisonment and drug injection addiction being significant risk factors. This study highlights the need for targeted interventions for these vulnerable populations.

    Area of Science:

    • Infectious Diseases
    • Hepatology
    • Virology

    Background:

    • Hepatitis B and C virus (HBV & HCV) infections are significant global health concerns.
    • Human immunodeficiency virus (HIV)-positive individuals are at increased risk of HBV and HCV co-infections.
    • Understanding risk factors for these co-infections is crucial for effective management and prevention.

    Purpose of the Study:

    • To determine the prevalence of hepatitis B and C virus co-infections among HIV-positive patients.
    • To identify demographic and behavioral risk factors associated with HBV and HCV co-infections in this population.

    Main Methods:

    • A cross-sectional study was conducted with 165 HIV-positive patients in Kerman, Iran.
    • Data on demographics and high-risk behaviors were collected.
    • Hepatitis C antibody and hepatitis B surface antigen were tested using ELISA; statistical analysis was performed using SPSS 18.

    Main Results:

    • The prevalence of HCV antibody was 73.9% and HBsAg was 3.6%.
    • Triple co-infection (HIV, HCV, HBV) was found in 1.8% of patients.
    • History of imprisonment (OR=17.5) and drug injection addiction (OR=15.3) were strongly associated with HCV co-infection.

    Conclusions:

    • HCV and HIV co-infection is highly prevalent in the studied population.
    • Imprisonment and drug injection addiction are significant risk factors for HCV/HIV co-infection.
    • These findings underscore the importance of targeted screening and prevention strategies.
    Abstract

    More Related Videos

    Detection of Low Copy Number Integrated Viral DNA Formed by In Vitro Hepatitis B Infection11:14

    Detection of Low Copy Number Integrated Viral DNA Formed by In Vitro Hepatitis B Infection

    Published on: November 7, 2018

    21.5K
    Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells09:02

    Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells

    Published on: June 5, 2020

    6.8K

    Related Concept Videos

    Hepatitis01:25

    Hepatitis

    Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver.
    86
    Viral Hepatitis I: Introduction01:28

    Viral Hepatitis I: Introduction

    Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion...
    25
    Sexually Transmitted Infections01:26

    Sexually Transmitted Infections

    Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
    2.0K
    Pulmonary Tuberculosis I01:29

    Pulmonary Tuberculosis I

    Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
    Causative Organism
    The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
    Mode of...
    1.7K
    Retrovirus Life Cycles01:10

    Retrovirus Life Cycles

    Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
    43.0K
    Infectious Diseases and Their Occurrence01:28

    Infectious Diseases and Their Occurrence

    Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable...
    94