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Updated: May 2, 2026
Identification of Neutrophil Extracellular Traps in Paraffin-Embedded Feline Arterial Thrombi using Immunofluorescence Microscopy
Published on: March 29, 2020
A case report of seronegative cat scratch disease, emphasizing the histopathologic point of view
Ok Ran Shin, Yang Ree Kim, Tae-hyun Ban
1Department of Hospital Pathology, Uijeongbu St, Mary's Hospital College of Medicine, The Catholic University of Korea 271, Cheonbo-ro, Uijeongbu-si, Gyenggi-do 480-717, Republic of Korea. ywacko@catholic.ac.kr.
Abstract:
Cat scratch disease, necrotizing granulomatous lymphadenitis caused by Bartonella henselae, usually benign and self-limited. However, various clinical manifestations and no pathognomonic histopathologic features can lead to misinterpretations and diagnostic disputes. We report a case of cat scratch disease in a 39-yr-old male patient with fever and left axillary lymphadenitis. He had a history of cat bite on the left hand dorsum. On excision, the lymph node showed follicular hyperplasia, stellate microabscesses with a rim of granulomatous inflammation. Warthin-Starry silver staining showed many clumps of silver-stained bacilli within the necrotic foci. Serological tests were negative. Diagnosis was established by PCR analysis.
Virtual Slides:
The virtual slides for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1877499238123059.
