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Updated: May 2, 2026

Structured Motor Rehabilitation After Selective Nerve Transfers
Published on: August 15, 2019
Radial nerve motor palsy following seasonal influenza vaccination: a case report
John S Taras1, Kenneth W Donohue
1The Philadelphia Hand Center, 834 Chestnut Street, Suite G-114, Philadelphia, PA 19107. jstaras@handcenters.com.
Abstract:
This case report describes the course of a 26-year-old male who developed a dense motor palsy of the radial nerve after receiving a seasonal influenza vaccination. The palsy developed within 12 to 16 hours of inoculation and demonstrated no clinical recovery until 5 months postinjury. Electromyographic and nerve conduction studies obtained at six weeks postinjury were consistent with complete motor denervation. Sensory function was preserved. The injury was successfully treated nonoperatively with physical therapy and wrist splinting, and the palsy gradually resolved over the next several months.
Insights
A rare case of radial nerve palsy occurred after an influenza vaccination. Nonoperative treatment with physical therapy led to gradual recovery over several months.
Area of Science:
- Neurology
- Immunology
- Vaccinology
Background:
- Seasonal influenza vaccinations are crucial for public health.
- Adverse events following vaccination are rare but important to document.
- Radial nerve palsy is a condition affecting arm and hand movement.
Observation:
- A 26-year-old male developed severe motor palsy of the radial nerve 12-16 hours post-influenza vaccination.
- Electromyography confirmed complete motor denervation with preserved sensory function.
- No recovery was observed until 5 months post-injury.
Findings:
- The radial nerve palsy was successfully managed nonoperatively.
- Treatment involved physical therapy and wrist splinting.
- Gradual resolution of the palsy occurred over several months.
Implications:
- This case highlights a potential, albeit rare, neurological complication of influenza vaccination.
- It underscores the importance of prompt diagnosis and conservative management for vaccine-associated nerve injuries.
- Further research may explore the immunopathological mechanisms linking vaccination to nerve palsy.
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