Radial nerve motor palsy following seasonal influenza vaccination: a case report

John S Taras1, Kenneth W Donohue

  • 1The Philadelphia Hand Center, 834 Chestnut Street, Suite G-114, Philadelphia, PA 19107. jstaras@handcenters.com.

Insights

A rare case of radial nerve palsy occurred after an influenza vaccination. Nonoperative treatment with physical therapy led to gradual recovery over several months.

Area of Science:

  • Neurology
  • Immunology
  • Vaccinology

Background:

  • Seasonal influenza vaccinations are crucial for public health.
  • Adverse events following vaccination are rare but important to document.
  • Radial nerve palsy is a condition affecting arm and hand movement.

Observation:

  • A 26-year-old male developed severe motor palsy of the radial nerve 12-16 hours post-influenza vaccination.
  • Electromyography confirmed complete motor denervation with preserved sensory function.
  • No recovery was observed until 5 months post-injury.

Findings:

  • The radial nerve palsy was successfully managed nonoperatively.
  • Treatment involved physical therapy and wrist splinting.
  • Gradual resolution of the palsy occurred over several months.

Implications:

  • This case highlights a potential, albeit rare, neurological complication of influenza vaccination.
  • It underscores the importance of prompt diagnosis and conservative management for vaccine-associated nerve injuries.
  • Further research may explore the immunopathological mechanisms linking vaccination to nerve palsy.

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