Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vaccinations01:51

Vaccinations

44.1K
Overview
44.1K
Symbiosis00:58

Symbiosis

27.8K
Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...
27.8K
Vaccines01:21

Vaccines

98
Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the...
98
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

1.3K
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Production of a novel cellulase by Bacillus amyloliquefaciens OKB3 isolated from soil: Purification and characterization.

International journal of biological macromolecules·2024
Same author

Higher coronavirus disease-19 mortality linked to comorbidities: A comparison between low-middle income and high-income countries.

Journal of education and health promotion·2021
Same author

Public health information systems for primary health care in India: A situational analysis study.

Journal of family medicine and primary care·2019
Same author

Study of Domestic Violence among Currently Married Females of Haryana, India.

Indian journal of psychological medicine·2018
Same author

Hypertension in Pregnancy: A Community-Based Study.

Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine·2015
Same author

Human papillomavirus vaccine: a boon or curse.

Human vaccines & immunotherapeutics·2015

Related Experiment Video

Updated: May 2, 2026

Myeloid Cell Isolation from Mouse Skin and Draining Lymph Node Following Intradermal Immunization with Live Attenuated Plasmodium Sporozoites
08:46

Myeloid Cell Isolation from Mouse Skin and Draining Lymph Node Following Intradermal Immunization with Live Attenuated Plasmodium Sporozoites

Published on: May 18, 2016

17.2K

Malaria vaccine: a step toward elimination.

Harashish Jindal1, Bhumika Bhatt1, Jagbir S Malik1

  • 1Department of Community Medicine; Pt BD Sharma PGIMS; Rohtak, Haryana India.

Human Vaccines & Immunotherapeutics
|March 20, 2014
PubMed
Summary

A malaria vaccine could significantly reduce illness and death, especially in children, by complementing existing control methods. Integration with the Expanded Programme on Immunization (EPI) would enhance accessibility and impact.

Keywords:
eliminationmalarianeedvaccine

More Related Videos

In Vitro Assay of Plasmodium-Infected Red Blood Cell Killing by Cytotoxic Lymphocytes
08:20

In Vitro Assay of Plasmodium-Infected Red Blood Cell Killing by Cytotoxic Lymphocytes

Published on: August 17, 2022

2.3K
Microinjection Method for Anopheles gambiae Embryos
05:39

Microinjection Method for Anopheles gambiae Embryos

Published on: July 7, 2021

4.5K

Related Experiment Videos

Last Updated: May 2, 2026

Myeloid Cell Isolation from Mouse Skin and Draining Lymph Node Following Intradermal Immunization with Live Attenuated Plasmodium Sporozoites
08:46

Myeloid Cell Isolation from Mouse Skin and Draining Lymph Node Following Intradermal Immunization with Live Attenuated Plasmodium Sporozoites

Published on: May 18, 2016

17.2K
In Vitro Assay of Plasmodium-Infected Red Blood Cell Killing by Cytotoxic Lymphocytes
08:20

In Vitro Assay of Plasmodium-Infected Red Blood Cell Killing by Cytotoxic Lymphocytes

Published on: August 17, 2022

2.3K
Microinjection Method for Anopheles gambiae Embryos
05:39

Microinjection Method for Anopheles gambiae Embryos

Published on: July 7, 2021

4.5K

Area of Science:

  • Global Health
  • Immunology
  • Parasitology

Background:

  • Malaria remains a major global health challenge, particularly in Africa, causing significant morbidity and mortality, especially in young children.
  • Current control strategies include vector control and antimalarial drugs, but an effective vaccine is needed to further reduce disease burden.
  • An estimated 3.4 billion people are at risk globally, with 80% of cases and 90% of deaths occurring in Africa.

Purpose of the Study:

  • To review the current status and future prospects of malaria vaccine development.
  • To highlight the potential impact of a licensed malaria vaccine on global public health.
  • To discuss the integration of malaria vaccination into existing immunization programs.

Main Methods:

  • Review of historical and ongoing malaria vaccine research and development efforts.
  • Analysis of clinical trial data for promising vaccine candidates, such as RTS,S/AS01.
  • Examination of global malaria burden statistics and public health intervention strategies.

Main Results:

  • Despite decades of research, no malaria vaccines are currently licensed.
  • The RTS,S/AS01 vaccine targeting Plasmodium falciparum shows promising results in Phase 3 clinical trials.
  • A malaria vaccine is envisioned by 2030 to reduce cases by 75% and aid elimination efforts.

Conclusions:

  • A malaria vaccine represents a critical, long-term tool for reducing malaria-related morbidity and mortality.
  • Vaccine integration with the Expanded Programme on Immunization (EPI) could improve accessibility and effectiveness.
  • Achieving a licensed, effective malaria vaccine by 2030 aligns with global health goals for disease reduction and potential elimination.