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Updated: May 2, 2026

Author Spotlight: Optimizing CFPS Systems for Synthetic Cell Construction
Published on: April 19, 2024
Cell-free protein synthesis: search for the happy middle
Zachary N Russ1, John E Dueber
1Department of Bioengineering, University of California, Berkeley, CA, USA; Energy Biosciences Institute, University of California, Berkeley, CA, USA.
Abstract:
Cell-free protein synthesis (CFPS) is a versatile technique gaining popularity because it allows researchers access to on-demand production of proteins. This Commentary by Zachary Russ and John Dueber discusses the latest research article by Rui Gan and Michael Jewett, which reports a convenient and cost-effective methodology for the preparation of Saccharomyces cerevisiae-based CFPS reactions.
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