Related Experiment Video
Updated: Feb 11, 2026

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
Published on: March 25, 2022
Primary obstructive megaureter in infants: our experience with endoscopic balloon dilation and cutting balloon
Nicola Capozza1, Giovanni Torino, Simona Nappo
1Surgical Unit of the Pediatric Urology, "Bambino Gesù" Children's Hospital and Research Institute , Rome, Italy .
Insights
Endoscopic treatment for primary obstructive megaureter (POM) shows promise. High-pressure balloon dilation and cutting balloon ureterotomy effectively resolved stenosis in most cases, offering a viable surgical option.
Area of Science:
- Pediatric Urology
- Minimally Invasive Surgery
- Endourology
Background:
- Primary obstructive megaureter (POM) management is often conservative in infants.
- High-grade POM with dilation, obstructive renography, or reduced renal function necessitates surgical intervention.
Purpose of the Study:
- To evaluate the efficacy of endoscopic management for primary obstructive megaureter.
- To assess the outcomes of endoscopic high-pressure balloon dilation (EHPBD) and cutting balloon ureterotomy (CBU) for POM.
Main Methods:
- Retrospective analysis of 12 patients (6-12 months old) treated endoscopically for POM between January 2009 and March 2013.
- Procedures included identification of stenotic rings, EHPBD, and CBU for persistent rings.
- Mean follow-up was 21 months.
Main Results:
- A stenotic ring was identified in 10 of 12 patients.
- EHPBD was successful in 7 patients.
- CBU for persistent rings resulted in complete stenosis resolution.
- Overall success rate for EHPBD+CBU was 83%.
Conclusions:
- Endoscopic treatment is a viable option for primary obstructive megaureter.
- CBU is an effective definitive treatment for POM with persistent rings unresponsive to EHPBD.
Abstract:
The management of primary obstructive megaureter (POM) is usually conservative, at least in the first year of life. Nevertheless, in high-grade POMs with increasing dilation, obstructive patterns found at renography, or cases involving decreased renal function, there is a clear indication for surgery. From January 2009 to March 2013, 12 patients, aged 6 to 12 months (mean 8 months), were treated endoscopically for POM. At the procedure, a clear stenotic ring was identified in 10 of the 12 patients, and a simple endoscopic high-pressure balloon dilation (EHPBD) was well performed in 7 patients. In the three cases with persistent ring, a cutting balloon ureterotomy (CBU) was then performed, resulting in the immediate and complete disappearance of the stenosis. In two cases, no ring could be seen at the procedure, and they showed no improvement at the follow-up. The mean follow-up was 21 months. Considering the whole series of patients treated endoscopically, the overall success rate of EHPBD+CBU was 83%. Patients with POM can be treated endoscopically. In the case of a persistent ring that is unresponsive to EHPBD, CBU seems to provide a valid definitive treatment of POM.
Related Concept Videos
Drug Dosing: Infants and Children
Cardiomyopathy II: Dilated Cardiomyopathy
Cut-off Frequency of BJT
Alpha Cut-Off Frequency: Pertinent to the common-base configuration, the alpha cut-off frequency defines the upper-frequency limit at which the current gain, alpha, remains stable. As...
Brick Cutting Techniques
Cut bricks are categorized by size. Bricks cut to half their original length are called half-bats, while those cut to three-fourths their length are known as three-fourth bats.
Special types of...
What is an Experiment?
Thomson's e/m Experiment
A particle with charge q, speed v, and mass m enters an area from the top, where the magnetic and electric fields are perpendicular both to the particle's motion and to one another. The magnetic...

