Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antibiotic Selection00:57

Antibiotic Selection

48.9K
Overview
48.9K
Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

90
Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within...
90
Development of Antibiotic Resistance01:30

Development of Antibiotic Resistance

2.0K
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
2.0K
Mechanism of Antibiotic Resistance in MRSA01:25

Mechanism of Antibiotic Resistance in MRSA

219
Antibiotic resistance in bacteria arises when microorganisms evolve the ability to withstand drugs designed to kill them or inhibit their growth, rendering once-effective treatments useless. This phenomenon, driven by genetic change and selection under antibiotic exposure, poses a profound threat to modern medicine. Mechanisms include drug-inactivating enzymes (e.g., β-lactamases), efflux pumps that eject antibiotics, mutations altering antibiotic targets, decreased drug uptake, and...
219
Biological Methods for Microbial Control01:28

Biological Methods for Microbial Control

1.4K
Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
1.4K
Production of Antibiotics01:27

Production of Antibiotics

265
Penicillin, one of the earliest and most widely used antibiotics, is produced industrially by the filamentous fungus Penicillium chrysogenum. Large stirred-tank bioreactors ranging from tens to hundreds of thousands of liters maintain tightly controlled temperature, pH, and dissolved oxygen conditions to support fungal metabolism and maximize antibiotic yield. Penicillin is a secondary metabolite, synthesized primarily during the stationary growth phase, which requires a carefully managed...
265

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bacterial sensitivity distributions for biocides and metals.

FEMS microbiology ecology·2026
Same author

Sewage surveillance for assessing clinical antibiotic resistance prevalence: Combining metagenomic and phenotypic data.

One health (Amsterdam, Netherlands)·2026
Same author

Author Correction: Geographics and bacterial networks differently shape the acquired and latent global sewage resistomes.

Nature communications·2026
Same author

Antibiotic surveillance: an action-oriented integrated approach.

Wellcome open research·2026
Same author

No Clear Evidence of Histopathological Effects Linked to NSAIDs in the Kidney or Liver of Fish Exposed to Treated Municipal Wastewaters.

Toxicologic pathology·2026
Same author

Antibiotic resistance gene analyses in microbial communities: challenges and opportunities.

Nature communications·2026

Related Experiment Video

Updated: May 2, 2026

Identification of Pharmaceuticals in The Aquatic Environment Using HPLC-ESI-Q-TOF-MS and Elimination of Erythromycin Through Photo-Induced Degradation
05:46

Identification of Pharmaceuticals in The Aquatic Environment Using HPLC-ESI-Q-TOF-MS and Elimination of Erythromycin Through Photo-Induced Degradation

Published on: August 1, 2018

15.4K

Antibiotics in the environment.

D G Joakim Larsson1

  • 1Department of Infectious Diseases, Institute for Biomedicine, The Sahlgrenska Academy at the University of Gothenburg , Guldhedsgatan 10, SE-413 46, Gothenburg , Sweden.

Upsala Journal of Medical Sciences
|March 21, 2014
PubMed
Summary

Antibiotic resistance is a growing threat, accelerated by widespread environmental antibiotic exposure. This review examines antibiotic environmental exposure routes, risks, and management strategies to mitigate resistance.

Keywords:
Antibiotic resistancebacteriaenvironmentpollutionrisk assessmentwaste-water

More Related Videos

Author Spotlight: Understanding and Detecting Environmental Antimicrobial Resistance by Combining Culture-Based Techniques and Genomics
06:54

Author Spotlight: Understanding and Detecting Environmental Antimicrobial Resistance by Combining Culture-Based Techniques and Genomics

Published on: July 19, 2024

2.0K
Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
08:58

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

Published on: March 3, 2023

8.8K

Related Experiment Videos

Last Updated: May 2, 2026

Identification of Pharmaceuticals in The Aquatic Environment Using HPLC-ESI-Q-TOF-MS and Elimination of Erythromycin Through Photo-Induced Degradation
05:46

Identification of Pharmaceuticals in The Aquatic Environment Using HPLC-ESI-Q-TOF-MS and Elimination of Erythromycin Through Photo-Induced Degradation

Published on: August 1, 2018

15.4K
Author Spotlight: Understanding and Detecting Environmental Antimicrobial Resistance by Combining Culture-Based Techniques and Genomics
06:54

Author Spotlight: Understanding and Detecting Environmental Antimicrobial Resistance by Combining Culture-Based Techniques and Genomics

Published on: July 19, 2024

2.0K
Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
08:58

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

Published on: March 3, 2023

8.8K

Area of Science:

  • Microbiology
  • Environmental Science
  • Public Health

Background:

  • Antibiotics, naturally produced by microbes, have long exerted selection pressure on bacteria.
  • Mass production of antibiotics in the 20th century led to widespread bacterial exposure and rapid resistance development.
  • Environmental antibiotic contamination poses risks beyond human-associated microbial communities.

Purpose of the Study:

  • To overview routes of antibiotic environmental exposure.
  • To discuss current knowledge on human and ecosystem risks.
  • To suggest management options for reducing environmental antibiotic risks.

Main Methods:

  • Literature review of antibiotic environmental exposure.
  • Synthesis of current knowledge on risks to humans and ecosystems.
  • Identification of potential risk management strategies.

Main Results:

  • Antibiotics enter the environment through various routes, often unintentionally.
  • Environmental antibiotic exposure can drive resistance gene recruitment to human pathogens.
  • Significant knowledge gaps exist regarding the full scope of environmental risks.

Conclusions:

  • Environmental antibiotic contamination is a critical factor in the rise of antibiotic resistance.
  • Addressing environmental exposure is crucial for mitigating the global antibiotic resistance crisis.
  • Integrated management strategies are needed to reduce antibiotic release into the environment.