Decomposition of tetrodotoxin using multi-gas plasma jet
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Updated: May 2, 2026

An Atmospheric Pressure Plasma Setup to Investigate the Reactive Species Formation
Published on: November 3, 2016
Toshihiro Takamatsu1, Hidekazu Miyahara, Takeshi Azuma
1Tokyo Institute of Technology, Department of Energy Sciences.
Abstract:
In this study, non-thermal multi-gas plasma treatments were performed for Tetrodotoxin (TTX) solution, and TTX decomposition was analyzed by liquid chromatography coupled with electrospray time-of-flight mass spectrometry. The TTX mass spectrum signal was reduced by plasma irradiations to different levels by using various gas species. Nitrogen plasma exhibited the optimal capability for TTX decomposition, followed by oxygen, argon, and carbon dioxide plasmas. The TTX concentration decreased 100-fold by nitrogen plasma treatment for 10 min.
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