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Arguments in the evo-devo debate: say it with flowers!
Serena Della Pina1, Erik Souer1, Ronald Koes2
1Department of Molecular Cell Biology, Graduate School of Experimental Plant Sciences, VU University, de Boelelaan 1085, 1081 HV Amsterdam, The Netherlands.
Journal of Experimental Botany
|March 21, 2014
Summary
Changes in DNA regulatory sequences, not just gene mutations, are key drivers of morphological diversity in evolution. This highlights the significant role of cis-regulatory sequences in shaping organismal form.
Area of Science:
- Evolutionary developmental biology
- Genetics
- Molecular biology
Background:
- Morphological diversity evolution is driven by DNA sequence changes.
- Historically, focus was on transcription factors and protein sequence alterations.
- Deeply conserved 'toolkit' genes control development; mutations often have negative effects.
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