Related Experiment Video
Updated: Jan 30, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
Published on: March 3, 2023
The emerging role of interleukin-21 in allergic diseases (Review)
Fang Gong1, Qiang Su2, Yu Hong Pan1
1Department of Laboratory Medicine, The Third Hospital Affiliated to Nantong University, Wuxi, Jiangsu 214041, P.R. China.
Abstract:
Interleukin (IL)-21 is a newly discovered member of the type I cytokine family. Since its discovery in 2000, IL-21 has been the focus of extensive investigation, due to its homology to IL-2, IL-4 and IL-15 and its pleiotropic effects on innate and adaptive immune responses. An increasing amount of experimental evidence supports a role for IL-21 in the pathogenesis of several allergic diseases, such as allergic rhinitis, atopic dermatitis (AD) and atopic asthma. In this review, we aimed to discuss the biological characteristics of IL-21 and summarize the current progress on the role of IL-21 in the regulation of allergic inflammation.
Related Concept Videos
Introduction Cardiac Emergencies
Allergic Reactions
Review and Preview
Percentiles are a type of fractile that partition data into...
Review and Preview
Emerging Adulthood
Allergic Drug Reactions

