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Related Experiment Video

Updated: May 2, 2026

Murine Ileocolic Bowel Resection with Primary Anastomosis

Murine Ileocolic Bowel Resection with Primary Anastomosis

Published on: October 29, 2014

Malignant bowel obstruction: A retrospective clinical analysis.

Jia-Hong Chen¹, Tzu-Chuan Huang¹, Ping-Ying Chang¹

¹Division of Hematology/Oncology, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 10114, Taiwan, R.O.C .

Molecular and Clinical Oncology

|March 21, 2014

Summary

Malignant bowel obstruction (MBO) management lacks consensus. Surgery improved quality of life, while chemotherapy and targeted therapy offered better survival for colorectal cancer patients with MBO.

Keywords:

bowel obstruction cancer

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Last Updated: May 2, 2026

Murine Ileocolic Bowel Resection with Primary Anastomosis

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Published on: October 29, 2014

A Mouse Model of Intestinal Partial Obstruction

A Mouse Model of Intestinal Partial Obstruction

Published on: March 5, 2018

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction

Published on: March 25, 2022

Area of Science:

Oncology
Gastroenterology
Palliative Care

Background:

Malignant bowel obstruction (MBO) presents a poor prognosis, especially in advanced cancers.
Optimal MBO treatment lacks consensus, with limited evidence on improving quality of life (QOL) or survival.

Purpose of the Study:

To analyze clinicopathological characteristics of MBO.
To evaluate the association between treatments and prognosis or QOL in MBO patients.

Main Methods:

Retrospective analysis of MBO cases from a medical center database (1995-2008).
Inclusion of clinicopathological data and treatment information.

Main Results:

Adenocarcinoma of the colon was the primary cause of MBO.
MBO as an initial symptom correlated with higher overall survival.
Surgical treatment improved QOL; chemotherapy and targeted therapy showed better survival and functional status in colorectal cancer patients compared to surgery alone or conservative treatment.
Hospice care effectively reduced pain and relieved symptoms in end-stage MBO patients.

Conclusions:

MBO requires tailored treatment strategies based on cancer type and stage.
Multimodality approaches, including palliative care, are crucial for managing MBO symptoms and improving patient outcomes.