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Related Experiment Video

Updated: May 2, 2026

Digital Spatial Profiling for Characterization of the Microenvironment in Adult-Type Diffusely Infiltrating Glioma
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Extradigital glomus tumor: A case report.

Ji-Sun Chun1, Ran Hong2, Jung-A Kim3

  • 1Department of Plastic Surgery, College of Medicine, Chosun University, Gwanju 501-759, Republic of Korea.

Molecular and Clinical Oncology
|March 21, 2014
PubMed
Summary

Glomus tumors are benign vascular growths. This case highlights an extradigital glomus tumor of the elbow, emphasizing the need for their consideration in diagnosing unusual skin lesions.

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Area of Science:

  • Dermatology
  • Pathology
  • Surgical Oncology

Background:

  • Glomus tumors are benign vascular neoplasms originating from glomus bodies.
  • Typically presenting as small, blue-red nodules on extremities, most commonly subungually.
  • Extradigital glomus tumors can present with atypical clinical features, complicating diagnosis.

Purpose of the Study:

  • To report a rare case of an extradigital glomus tumor.
  • To discuss diagnostic challenges associated with extradigital glomus tumors.
  • To underscore the importance of including glomus tumors in the differential diagnosis of unusual subcutaneous lesions.

Main Methods:

  • Case report of a 45-year-old patient with an elbow subcutaneous tumor.
  • Histopathological examination of the tumor.
Keywords:
elbowglomus tumor

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  • Immunohistochemical analysis for smooth muscle actin (SMA) and vimentin (VMT).
  • Main Results:

    • Histopathology confirmed a well-circumscribed nodule with characteristic glomus tumor morphology.
    • Tumor cells showed positive reactivity for SMA and VMT.
    • The tumor was located in the subcutaneous tissue of the elbow, an extradigital site.

    Conclusions:

    • Extradigital glomus tumors, though rare, require high clinical suspicion due to variable presentations.
    • Accurate diagnosis through histopathology and immunohistochemistry is crucial for appropriate management.
    • Simple excision is often curative for glomus tumors, but early diagnosis is key, especially for extradigital variants.