Related Experiment Video

Updated: May 2, 2026

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
09:05

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation

Published on: October 20, 2016

19.3K

Three-dimensional speckle tracking echocardiography allows detailed evaluation of left atrial function in

Péter Domsik1, Anita Kalapos, Számi Chadaide

  • 12nd Department of Medicine and Cardiology Center, Medical Faculty, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary.

Echocardiography (Mount Kisco, N.Y.)
|March 22, 2014
PubMed

Insights

Hypertrophic cardiomyopathy (HCM) significantly alters left atrial (LA) function, increasing its volume and reducing strain. Three-dimensional speckle tracking echocardiography (3DSTE) effectively quantifies these changes in HCM patients compared to controls.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Echocardiography

Background:

  • Hypertrophic cardiomyopathy (HCM) is a generalized myopathic condition affecting the heart's muscle.
  • Reduced left atrial (LA) function is a known characteristic of HCM, assessed through various methods.
  • Three-dimensional speckle tracking echocardiography (3DSTE) is a novel technique for evaluating LA function.

Purpose of the Study:

  • To compare LA volumetric and strain parameters derived from 3DSTE in HCM patients versus healthy controls.
  • To assess the utility of 3DSTE in detecting functional abnormalities of the left atrium in HCM.

Main Methods:

  • The study included 23 HCM patients and 23 age- and gender-matched healthy controls.
  • Both two-dimensional Doppler echocardiography and 3DSTE were performed on all participants.
  • LA volumes, atrial stroke volumes, and emptying fractions were calculated.

Main Results:

  • HCM patients exhibited significantly increased LA maximum, minimum, and pre-atrial contraction volumes compared to controls.
  • Atrial stroke volumes were elevated, while emptying fractions were reduced in HCM patients.
  • Mean global radial, longitudinal, and 3D strain parameters were significantly reduced in HCM patients.

Conclusions:

  • Three-dimensional speckle tracking echocardiography provides a detailed assessment of left atrial function in hypertrophic cardiomyopathy.
  • 3DSTE enables precise volumetric and strain measurements for evaluating LA (dys)function in HCM.
Abstract

Keywords:
echocardiographyfunctionhypertrophic cardiomyopathyleft atriumspeckle trackingthree-dimensional

More Related Videos

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography06:34

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

4.1K
High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart11:50

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart

Published on: July 9, 2010

25.4K

Related Concept Videos

Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
805
Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
557
Imaging Studies for Cardiovascular System II:Types of Echocardiography01:20

Imaging Studies for Cardiovascular System II:Types of Echocardiography

Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
964
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
1.3K