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Updated: May 2, 2026

Open-source Single-particle Analysis for Super-resolution Microscopy with VirusMapper
Published on: April 9, 2017
Super-resolution microscopy: a virus' eye view of the cell
1Institute of Immunity and Transplantation, University College London, London NW3 2PF, UK. j.grove@ucl.ac.uk.
Abstract:
It is difficult to observe the molecular choreography between viruses and host cell components, as they exist on a spatial scale beyond the reach of conventional microscopy. However, novel super-resolution microscopy techniques have cast aside technical limitations to reveal a nanoscale view of virus replication and cell biology. This article provides an introduction to super-resolution imaging; in particular, localisation microscopy, and explores the application of such technologies to the study of viruses and tetraspanins, the topic of this special issue.
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