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Trends in in-hospital mortality among patients with stroke in China
Qian He1, Cheng Wu1, Hong Luo2
1Department of Health Statistics, Second Military Medical University, Shanghai, China.
Insights
Stroke in-hospital mortality in China decreased from 3.16% to 2.30% between 2007 and 2010, despite an increase in severe cases. Advancements in stroke care likely contributed to this positive trend.
Area of Science:
- Neurology
- Public Health
- Epidemiology
Background:
- Stroke incidence and burden are rising in China.
- In-hospital mortality trends for stroke patients in China are not well understood.
- This study addresses the need to analyze stroke mortality during hospitalization in China.
Purpose of the Study:
- To assess trends in in-hospital mortality among stroke patients in China.
- To identify factors influencing in-hospital death after stroke.
Main Methods:
- A multistage stratified cluster sampling method was used to select 109 grade III class A hospitals.
- Data from patients hospitalized with a stroke diagnosis between 2007 and 2010 were analyzed.
- Multivariable logistic regression was employed to explore factors associated with in-hospital death.
Main Results:
- Stroke hospitalizations increased from 79,894 in 2007 to 85,475 in 2010.
- In-hospital mortality for stroke decreased significantly from 3.16% to 2.30% (P<0.0001).
- Factors associated with higher in-hospital mortality included older age, male sex, basic health insurance, multiple comorbidities, and disease severity.
Conclusions:
- The decline in stroke in-hospital mortality suggests improvements in stroke care and prevention strategies.
- The simultaneous increase in severe stroke cases highlights the need for enhanced focus on rehabilitation and quality of life.
- Individual and hospital-level characteristics present targets for further reducing stroke mortality.
Background:
The incidence and burden of stroke in China is increasing rapidly. However, little is known about trends in mortality during stroke hospitalization. The objectives of this study were to assess trends of in-hospital mortality among patients with stroke and explore influence factors of in-hospital death after stroke in China.
Methods:
109 grade III class A hospitals were sampled by multistage stratified cluster sampling. All patients admitted to hospitals between 2007 and 2010 with a discharge diagnosis of stroke were included. Trends in in-hospital mortality among patients with stroke were assessed. Influence factors of in-hospital death after stroke were explored using multivariable logistic regression.
Results:
Overall stroke hospitalizations increased from 79,894 in 2007 to 85,475 in 2010, and in-hospital mortality of stroke decreased from 3.16% to 2.30% (P<0.0001). The percentage of severe patients increased while odds of mortality (2010 versus 2007) decreased regardless of stroke type: subarachnoid hemorrhage (OR 0.792, 95% CI = 0.636 to 0.987), intracerebral hemorrhage (OR 0.647, 95% CI = 0.591 to 0.708), and ischemic stroke (OR 0.588, 95% CI = 0.532 to 0.649). In multivariable analyses, older age, male, basic health insurance, multiple comorbidities and severity of disease were linked to higher odds of in-hospital mortality.
Conclusions:
The mortality of stroke hospitalizations decreased likely reflecting advancements in stroke care and prevention. Decreasing of mortality with increasing of severe stroke patients indicated that we should pay more attention to rehabilitation and life quality of stroke patients. Specific individual and hospital-level characteristics may be targets for facilitating further declines.
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