Related Experiment Video
Updated: May 2, 2026

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
Published on: May 2, 2025
Clinical factors associated with the diagnosis and progression of diabetic nephropathy
Shuang Liang1, Qian Li, Han-Yu Zhu
1Department of Nephrology, State Key Laboratory of Kidney Diseases, Chinese PLA General Hospital, Beijing, 100853, China.
Abstract:
As an important complication of diabetic mellitus, diabetic nephropathy (DN) has been the main cause of end-stage renal disease. It is of great importance to diagnose DN early, and to identify the risk factors of disease progression in order to carry out in-time and effective therapies. Previous literatures have reported the role of several clinical factors in the diagnosis and progression of DN, including age, longer diabetes duration, diabetic retinopathy, higher level of hypertension and HbA1c, and so on. However, the significance of these clinical factors is still controversial and limited. This review aimed to evaluate the values and limitations of these factors in diagnosing and predicting the renal outcome of DN.
Related Concept Videos
Diabetic Nephropathy
Chronic Kidney Disease I: Introduction
Diabetic Retinopathy
Diabetic Neuropathy
Chronic Kidney Disease II: Clinical Manifestations
Diabetes: Symptoms, Diagnosis, and Complications

