Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Drug Administration and Therapy Phases: Overview

Drug Administration and Therapy Phases: Overview

Drugs, the chemical agents used in diagnosing, treating, or preventing diseases, undergo a four-phase process of development: pharmaceutic, pharmacokinetics, pharmacodynamics, and therapeutic.
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...

Drug Abuse and Addiction: Pharmacological Phenomena

Drug Abuse and Addiction: Pharmacological Phenomena

Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...

Drug Control Governance: Regulatory Bodies and Their Impact

Drug Control Governance: Regulatory Bodies and Their Impact

Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with...

Levels of Health Promotion and Illness Prevention

Levels of Health Promotion and Illness Prevention

Health promotion allows a person to control the determinants of health, resulting in an improved health status. It enhances the quality of life and reduces premature deaths. Health promotion and illness prevention programs help people make beneficial choices to reduce the risk of disease and disabilities. There are three health promotion and illness prevention levels: primary, secondary, and tertiary prevention.
In primary prevention, actions taken before disease onset prevent the disease from...

Drug Discovery: Overview

Drug Discovery: Overview

Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...

Prodrugs

Prodrugs

Prodrugs are a class of pharmaceutical compounds that undergo a biotransformation process within the body to be converted into a pharmacologically active drug. Prodrugs are designed to improve the therapeutic properties of the parent drug, such as enhancing bioavailability, increasing stability, or reducing toxicity. The concept of prodrugs revolves around modifying the chemical structure of the original drug to make it more effective or convenient for administration.
Prodrugs help overcome...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A National Strategy for Preventing Substance and Opioid Use Disorders Through Evidence-Based Prevention Programming That Fosters Healthy Outcomes in Our Youth.

Focus (American Psychiatric Publishing)·2024

Same author

Effects of the Universal Prevention Curriculum for Schools on Substance Use Among Peruvian Adolescents: A Randomized Trial.

Journal of drug education·2023

Same author

Normalization of Prevention Principles and Practices to Reduce Substance Use Disorders Through an Integrated Dissemination and Implementation Framework.

Prevention science : the official journal of the Society for Prevention Research·2023

Same author

A National Strategy for Preventing Substance and Opioid Use Disorders Through Evidence-Based Prevention Programming that Fosters Healthy Outcomes in Our Youth.

Clinical child and family psychology review·2022

Same author

Commentary on the Culture of Prevention.

Prevention science : the official journal of the Society for Prevention Research·2020

Same author

Implementation of Screening, Brief Intervention, and Referral for Treatment in the Aging Network of Care to Prevent Alcohol, Recreational Drug, and Prescription Medication Misuse.

Prevention science : the official journal of the Society for Prevention Research·2020

Search research articles

Related Experiment Video

Updated: May 2, 2026

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

Published on: January 5, 2018

Reconceptualizing drug use prevention processes.

|March 22, 2014

Summary

Advancing drug use prevention requires integrating behavioral theories, understanding risk factors, and using sophisticated research. This reconceptualization refines interventions for better outcomes.

Area of Science:

Behavioral Science
Neuroscience
Public Health

Background:

Drug use prevention has evolved through integrated behavioral theories and enhanced understanding of onset factors.
Sophisticated research methodologies in study design, measurement, and data analysis have advanced the field.
Recent neurobiological and developmental insights inform our understanding of individual vulnerability and environmental interactions.

Discussion:

A reconceptualization of prevention's intent and function is necessary for refining intervention development and implementation.
The review focuses on drug use prevention, with implications for other behavioral outcome prevention.
Concepts are informed by advances in neurobiological development and the interplay of vulnerability and environment.

Key Insights:

More Related Videos

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

Published on: December 11, 2016

Novel Apparatus and Method for Drug Reinforcement

Novel Apparatus and Method for Drug Reinforcement

Published on: August 20, 2010

Related Experiment Videos

Last Updated: May 2, 2026

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

Published on: January 5, 2018

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

Published on: December 11, 2016

Novel Apparatus and Method for Drug Reinforcement

Novel Apparatus and Method for Drug Reinforcement

Published on: August 20, 2010

Integration of behavioral theories and risk factor understanding is crucial for effective drug use prevention.
Advanced research methodologies enhance the precision and impact of prevention strategies.
Understanding neurobiological development and socio-environmental interactions is key to personalized prevention.

Outlook:

Future prevention efforts should leverage neurobiological and socialization concepts for tailored interventions.
Refined intervention development and implementation strategies will improve public health outcomes.
The principles discussed have broad applicability to preventing various at-risk behaviors.