Gold nanoparticles displaying tumor-associated self-antigens as a potential vaccine for cancer immunotherapy

Sukyung Ahn1, In-Hyun Lee, Sukmo Kang

  • 1KAIST Institute for the BioCentury, Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 305-701, South Korea.

Golden vaccine for cancers. Gold nanoparticles enable efficient antigen delivery to dendritic cells and then activate the cells to facilitate cross-presentation, inducing antigen-specific cytotoxic T-lymphocyte responses for effective cancer therapy.

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