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Updated: May 2, 2026

Mechanical Separation and Protein Solubilization of the Outer and Inner Perivitelline Sublayers from Hen's Eggs
Published on: January 27, 2021
Application and bioactive properties of proteins and peptides derived from hen eggs: opportunities and challenges
Zhipeng Yu1, Yongguang Yin, Wenzhu Zhao
1College of Chemistry, Chemical Engineering and Food Safety, Bohai University, Jinzhou, 121013, China; Department of Food, Nutrition and Packaging Sciences, Clemson University, Clemson, SC, 29634, USA.
Abstract:
Several proteins and peptides that are released in vitro and/or in vivo from hen eggs are biologically active and have a variety of functional properties in humans beyond normal nutrition, for which extensive studies have been performed. This review focuses on their biological activities, including antihypertensive, antioxidant, antimicrobial, antiadhesive, immunomodulatory and antithrombotic activities and enhancement of mineral absorption. These proteins and peptides have been shown to regulate the nervous system, cardiovascular system, immune system and gastrointestinal system. The potential application and future directions of research on these bioactive peptides and proteins in the food industry are also addressed.
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