Related Experiment Video
Updated: May 2, 2026
06:32
Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats
Published on: June 28, 2019
7.7K
Fractional flow reserve: an updated review
Islam Y Elgendy1, C Richard Conti, Anthony A Bavry
1Department of Medicine, University of Florida College of Medicine, Gainesville, Florida.
Clinical Cardiology
|March 22, 2014
Summary
Fractional flow reserve (FFR) helps identify significant coronary artery blockages. This invasive measurement guides revascularization decisions, improving patient management when noninvasive tests are inconclusive.
Area of Science:
- Cardiology
- Interventional Cardiology
- Physiology
Background:
- Coronary artery disease management often involves revascularization.
- Conventional angiography can overestimate lesion severity, leading to unnecessary interventions.
- Accurate assessment of coronary physiology is crucial for optimal treatment.
Purpose of the Study:
- To review the concept and clinical utility of Fractional Flow Reserve (FFR).
- To discuss the evidence supporting FFR in guiding revascularization decisions.
- To explore future perspectives for FFR application in coronary artery disease.
Main Methods:
- Review of current literature on Fractional Flow Reserve (FFR).
- Analysis of studies comparing FFR diagnostic accuracy with noninvasive modalities.
- Examination of clinical outcome data from studies using FFR-guided treatment strategies.
Main Results:
- FFR is a valuable tool for assessing the hemodynamic significance of coronary lesions.
- European Society of Cardiology guidelines recommend FFR for guiding revascularization when noninvasive data is lacking.
- FFR-guided strategies have demonstrated clinical utility in managing intermediate coronary stenoses.
Conclusions:
- FFR provides critical physiological information beyond anatomical assessment.
- Accurate FFR measurement aids in selecting appropriate patients for revascularization.
- Further research will continue to refine the role of FFR in interventional cardiology.
More Related Videos
Related Concept Videos
01:24Rapidly Varying Flow
731
Rapidly varying flow (RVF) in open channels is characterized by abrupt changes in flow depth over a short distance, with the rate of depth change relative to distance often approaching unity. These flows are inherently complex due to their transient and multi-dimensional nature, making exact analysis difficult. However, approximate solutions using simplified models provide valuable insights into their behavior.Key Features of Rapidly Varying FlowRVF is commonly observed in scenarios involving...
731
01:19Urodynamic Studies: Uroflowmetry
9.4K
Uroflowmetry is a non-invasive urodynamic test designed to measure various aspects of urination, including volume, flow rate, and the time to void. This test is crucial for diagnosing and assessing conditions such as bladder outlet obstruction, bladder dysfunction, incomplete bladder emptying, incontinence, and urinary tract blockages caused by benign prostatic hyperplasia (BPH) and urethral strictures.Pre-Test Instructions:Before a uroflowmetry test, patients are typically advised to drink...
9.4K
01:16Conservation of Mass in Finite Cotrol Volume
1.6K
The principle of conservation of mass is a fundamental law in fluid mechanics and is applied using the continuity equation. We apply the concept to a finite control volume to derive the continuity equation.
A system is defined as a collection of unchanging contents, and the conservation of mass states that a system's mass is constant.
A system is defined as a collection of unchanging contents, and the conservation of mass states that a system's mass is constant.
1.6K
01:09The Buckingham Pi Theorem
2.0K
The Buckingham Pi theorem provides a structured method to simplify fluid dynamics problems by reducing complex systems of variables to dimensionless terms.
2.0K
01:10Poiseuille's Law and Reynolds Number
8.2K
Any fluid in a horizontal tube can flow due to pressure differences—fluid flows from high to low pressure. The flow rate (Q) is the ratio of pressure difference and resistance through a horizontal tube. The greater the pressure difference, the higher the flow rate. The flow resistance is expressed as:
8.2K
01:29Gradually Varying Flow
700
Gradually varying flow (GVF) in open channels describes situations where water depth changes slowly along the channel due to factors like non-uniform bed slope, channel shape variations, or obstructions. This flow type occurs when the depth adjusts gradually to balance gravitational forces, shear forces, and energy requirements, resulting in a low rate of depth change.Characteristics of Gradually Varying FlowGVF is commonly observed in natural streams, rivers, and canals, where flow depth...
700