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A study on the effect of resveratrol on lipid metabolism in hyperlipidemic mice
Hui-chun Xie1, Hong-Ping Han1, Zhi Chen2
1The Key Laboratory of Education Ministry on Environments and Resources in Tibetan Plateau, Qinghai-Normal University, 38 West Wusi Road, Xining, 810008 ; Shaanxi Normal University, 199 South Chang'an Road, Xi'an, 710062.
Background:
The content of resveratrol is relatively high in Polygonum cuspidatum Sieb. et Zucc., and the resveratrol has the effect of blood vessel dilating, microcirculation improving, platelet aggregation inhibiting and anti-cancer. The objective of this paper was to study the effect of resveratrol on lipid metabolism in hyperlipidemia mice.
Materials And Methods:
Through the establishment of an experimental mouse model of hyperlipidemia, the effect of resveratrol on change in total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-c), and low-density lipoprotein cholesterol (LDL-c) levels in mouse serum were determined.
Results:
Resveratrol group can apparently reduce TC, TG, LDL-c and AI of hyperlipidemic mice in a dose effect manner.
Conclusion:
We concluded that resveratrol can effectively reduce blood lipid levels of hyperlipidemic mice.
