A case report of acute myocardial infarction concomitant with Standford type B aortic dissection

Ziyu Zheng1, Zi Ye1, Yingxiong Huang1

  • 1Department of Emergency Medicine, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, PR China.

Insights

Misdiagnosing aortic dissection (AD) as acute myocardial infarction (AMI) can be fatal. Early AD detection using risk scores, echocardiography, and D-dimer is crucial before AMI reperfusion therapy.

Area of Science:

  • Cardiology
  • Vascular Surgery

Background:

  • Acute myocardial infarction (AMI) and aortic dissection (AD) co-occurrence is rare but critical.
  • Misdiagnosis as AMI can lead to inappropriate anticoagulant or thrombolytic therapy, worsening outcomes.
  • Stanford type B AD is particularly infrequent in conjunction with AMI.

Purpose of the Study:

  • To highlight a case of diagnostic error due to apparent concordance of AMI symptoms.
  • To emphasize the importance of considering AD in AMI patients.

Main Methods:

  • Case presentation of an 85-year-old male with hypertension and coronary artery disease.
  • Initial diagnosis of non-ST-segment elevation myocardial infarction based on symptoms, enzymes, and ECG.
  • Coronary angiography revealed significant stenosis treated with stents.
  • Computed tomography angiography identified concomitant Stanford type B AD due to persistent symptoms.

Main Results:

  • The patient initially presented with symptoms suggestive of AMI.
  • Coronary angiography confirmed significant coronary artery stenosis, leading to stent placement.
  • Post-procedure, computed tomography angiography revealed an undiagnosed Stanford type B aortic dissection.
  • The patient refused further intervention and died from hemorrhagic shock.

Conclusions:

  • Aortic dissection can precipitate AMI through indirect mechanisms.
  • Thorough investigation for AD is essential before initiating reperfusion therapy for suspected AMI.
  • Tools like the Aortic Dissection Detection Risk Score, transthoracic echocardiography, and D-dimer aid in early AD identification.
Abstract

Related Concept Videos

Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
1.2K
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
1.6K
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
589
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
478
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
650
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
2.1K