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Non-steroidal anti-inflammatory drug - induced transient reactive papulotranslucent acrokeratoderma
O A Orzan1, L G Popa2, V Voiculescu3
1"Carol Davila" University of Medicine and Pharmacy, Bucharest ; "Elias" Emergency Hospital, Department of Dermatology.
Journal of Medicine and Life
|March 22, 2014
Summary
Transient reactive papulotranslucent acrokeratoderma (TRPA) is a rare skin condition causing temporary white papules on palms after water exposure. This case report details TRPA triggered by non-steroidal anti-inflammatory drug use, exploring its causes and treatments.
Area of Science:
- Dermatology
- Pharmacology
Background:
- Transient reactive papulotranslucent acrokeratoderma (TRPA) is an uncommon dermatosis.
- It presents as transient, symmetric, edematous white papules on the palms.
- Eccrine duct prominence is a characteristic feature.
Observation:
- A 28-year-old woman presented with symptoms of TRPA.
- The condition was triggered by the use of a non-steroidal anti-inflammatory drug (NSAID).
Findings:
- This case highlights a novel NSAID-induced etiology for TRPA.
- The rapid and transient nature of the papules was noted.
Implications:
- Understanding drug-induced TRPA expands differential diagnoses for palmar conditions.
- Further research into NSAID-induced TRPA pathophysiology is warranted.
- This finding may influence future NSAID prescribing practices.
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