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Technique of Porcine Liver Procurement and Orthotopic Transplantation using an Active Porto-Caval Shunt
Published on: May 7, 2015
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Modified technique for aortic cross-clamping during liver donor procurement.
Chirag S Desai1, Raffaele Girlanda, Jason Hawksworth
1Medstar Georgetown Transplant Institute, Washington, DC, USA.
Clinical Transplantation
|March 25, 2014
Summary
A novel surgical approach to the supraceliac aorta during liver procurement minimizes vascular damage, especially in pediatric and obese donors. This technique enhances donor organ safety and reduces graft loss from hepatic artery thrombosis.
Area of Science:
- Surgical Techniques
- Organ Procurement
- Vascular Surgery
Background:
- Vascular damage during organ procurement, particularly to the hepatic artery (HA), can lead to graft loss.
- Conventional dissection for supraceliac aorta exposure poses risks, especially in pediatric and obese donors with delicate or small anatomical spaces.
- Replaced or accessory left hepatic arteries (R/A LHA) are particularly vulnerable to damage with standard techniques.
Purpose of the Study:
- To describe a modified surgical technique for exposing the supraceliac aorta during liver procurement.
- To enhance the safety and ease of organ procurement, particularly for challenging donor types.
- To reduce the incidence of vascular injury and subsequent graft loss.
Main Methods:
- A modified approach to the supraceliac aorta from the left side, behind the gastroesophageal junction, avoiding division of the gastrohepatic ligament.
- Application of this technique in 104 liver procurements between May 2007 and May 2013.
- Inclusion of adult and pediatric donors, with specific attention to those with R/A LHA.
Main Results:
- No donor organs sustained damage during procurement using the modified technique.
- The technique was applied to 104 liver procurements, including 15 pediatric donors and 23 donors with R/A LHA.
- One adult recipient experienced HA thrombosis, unrelated to the procurement technique.
Conclusions:
- The described technical modification improves the safety of cadaveric liver procurement.
- This approach facilitates easier and safer exposure of the supraceliac aorta, reducing the risk of vascular injury.
- The technique is particularly beneficial for pediatric and obese donors, as well as those with anatomical variations like R/A LHA.
Keywords:
accessory left hepatic arterydonor operationhepatic arteryhepatic artery thrombosisleft hepatic arteryliver graftsliver transplantationorgan procurementreplaced left hepatic artery
