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Related Experiment Video

Updated: May 1, 2026

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Acupuncture for functional dyspepsia: study protocol for a two-center, randomized controlled trial.

Gajin Han, Seok-Jae Ko, Jae-Woo Park

  • 1Acupuncture and Meridian Science Research Center, College of Korean Medicine, Kyung Hee University, Kyung Hee dae-ro 26, Dongdaemun-gu, Seoul 130-701, South Korea. erc633@khu.ac.kr.

Trials
|March 25, 2014
PubMed
Summary

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This study investigated acupuncture for functional dyspepsia (FD). Results will show if acupuncture improves FD symptoms and clarify its mechanisms.

Area of Science:

  • Gastroenterology
  • Integrative Medicine
  • Clinical Trials

Background:

  • Functional dyspepsia (FD) is a prevalent condition lacking optimal treatments.
  • Acupuncture is a traditional therapy explored for FD symptom management.
  • This study evaluates acupuncture's efficacy in improving FD symptoms.

Purpose of the Study:

  • To assess the effectiveness of acupuncture in treating functional dyspepsia.
  • To explore potential mechanisms underlying acupuncture's therapeutic effects in FD.

Main Methods:

  • A two-center, randomized, waitlist-controlled trial involving 76 participants (aged 18-75) diagnosed with FD.
  • Participants received 8 sessions of acupuncture over 4 weeks or were waitlisted.
  • Outcomes included symptom response, Nepean dyspepsia index, quality of life, depression, anxiety, and ghrelin levels.

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Main Results:

  • Primary outcome: proportion of responders with adequate symptom relief.
  • Secondary outcomes: changes in validated questionnaires and ghrelin hormone levels.
  • Follow-up at 8 weeks to assess sustained effects.

Conclusions:

  • Findings will determine if acupuncture provides symptomatic benefit for FD patients.
  • The study aims to elucidate the mechanisms through which acupuncture may alleviate FD symptoms.