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Management of tardive syndromes with clozapine: a case series
Sandeep Grover1, Nandita Hazari1, Natasha Kate1
1Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
Abstract:
Tardive syndromes are among the most debilitating side effects associated with use of antipsychotics. In this case series we present 5 cases of drug induced tardive syndromes, who had not responded to many of the other therapeutic measures but responded to clozapine. The response rate with clozapine varied from 50% to 100% and the response was seen by week 3 in most cases. Over the long term follow-up of as long as 6 years the response to clozapine was sustained. In two cases clozapine could be stopped.
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