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Updated: May 1, 2026

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
Indicated and selective preventive interventions
Meghan L Marsac1, Katharine Donlon2, Steven Berkowitz3
1Department of Pediatrics, Center for Injury Research and Prevention, The Children's Hospital of Philadelphia, 3535 Market Street, Philadelphia, PA 19104, USA; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, 3451 Walnut Street, Philadelphia, PA 19104, USA.
Insights
Children exposed to trauma may develop posttraumatic stress symptoms (PTSS), impacting long-term outcomes. Family-centered interventions show promise for prevention, though more research is needed for best practices.
Area of Science:
- Child psychology
- Trauma studies
- Pediatric mental health
Background:
- Traumatic events pose a significant risk for children developing posttraumatic stress symptoms (PTSS).
- These symptoms can lead to adverse long-term functional outcomes.
- Research into risk factors and preventive interventions for pediatric PTSS is ongoing.
Purpose of the Study:
- To review the current understanding of risk factors for persistent PTSS in children.
- To evaluate the evidence for preventive interventions for pediatric PTSS.
- To identify gaps in current research and guide future studies.
Main Methods:
- Literature review of existing research on pediatric PTSS risk factors.
- Analysis of evidence for psychological and pharmacological interventions.
- Synthesis of findings to assess the state of preventive practices.
Main Results:
- Family-centered interventions, including psychoeducation and parent-child communication, show promise.
- Morphine is the only pharmacologic intervention with sufficient evidence in children.
- Evidence for preventive interventions is still developing.
Conclusions:
- Family-centered approaches are promising for preventing PTSS in children.
- Further research is essential to establish evidence-based, gold-standard preventive practices.
- Targeted interventions are needed to mitigate the long-term effects of trauma on children.
Abstract:
Exposure to traumatic events places children at risk for developing distressing, significant emotional reactions such as posttraumatic stress symptoms (PTSS). These reactions also affect long-term functional outcomes. Research on identified and potential risk factors for the development of significant, persistent PTSS is under way. Evidence for preventive interventions is in its infancy but progressing. Family-centered interventions comprising education about emotional reactions to traumatic events and focusing on communication between children and parents show promising results. Only morphine has shown sufficient evidence as a pharmacologic intervention in children. Additional research is necessary to support the establishment of gold-standard preventive practices.
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