Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 1, 2026

Three-dimensional Optical-resolution Photoacoustic Microscopy
08:31

Three-dimensional Optical-resolution Photoacoustic Microscopy

Published on: May 3, 2011

17.6K

A cost-efficient frequency-domain photoacoustic imaging system.

Peter Leboulluec1, Hanli Liu1, Baohong Yuan1

  • 1Department of Bioengineering, The University of Texas at Arlington, Arlington, TX 76019, USA, Joint Biomedical Engineering Program, The University of Texas at Arlington and The University of Texas Southwestern Medical Center at Dallas, TX 75390, USA.

American Journal of Physics
|March 25, 2014
PubMed
Summary

A cost-effective frequency domain photoacoustic (PA) imaging system is presented. This system enables noninvasive biological tissue imaging and offers hands-on learning for PA signal detection and underlying mechanisms.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exosomes from IL-33-Stimulated Macrophages Regulate Epithelial Barrier Function to Ameliorate TNBS-Induced Colitis in Mice.

Cells·2026
Same author

Data-driven wavelet coherence approach to assess neurovascular coupling in neonatal hypoxic-ischemic encephalopathy.

Neurophotonics·2026
Same author

Cerebrovascular-CSF coupling measured by broadband near-infrared spectroscopy as a physiological marker of brain aging and Alzheimer's disease.

Frontiers in aging neuroscience·2026
Same author

Dynamic models for ultrasound-switchable fluorescence.

Physics in medicine and biology·2026
Same author

The near-infrared diffuse correlation spectroscopy muscle perfusion index in human calf muscle: accounting for changes in hemoconcentration.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same author

CDK4 inhibition by luteolin enhances lenvatinib sensitivity in HCC via Wnt/β-catenin modulation.

Cancer cell international·2026

Area of Science:

  • Biomedical Optics
  • Acoustic Imaging
  • Medical Physics

Background:

  • Photoacoustic (PA) imaging is a powerful noninvasive technique for biological tissue visualization.
  • Traditional time-domain PA systems utilize expensive nanosecond pulsed lasers, limiting accessibility in educational settings.
  • Frequency-domain PA imaging offers a lower-cost alternative using intensity-modulated light sources.

Purpose of the Study:

  • To describe a simple and affordable frequency-domain photoacoustic imaging system.
  • To demonstrate the imaging capabilities of the developed system.
  • To provide educational opportunities for learning PA signal detection and mechanisms.

Main Methods:

  • Development of a cost-effective frequency-domain photoacoustic imaging system.
Keywords:
Frequency-domainLock-in AmplifierPhotoacoustic effect

More Related Videos

Hand-held Clinical Photoacoustic Imaging System for Real-time Non-invasive Small Animal Imaging
09:43

Hand-held Clinical Photoacoustic Imaging System for Real-time Non-invasive Small Animal Imaging

Published on: October 16, 2017

10.4K
A High-performance Compact Photoacoustic Tomography System for In Vivo Small-animal Brain Imaging
05:32

A High-performance Compact Photoacoustic Tomography System for In Vivo Small-animal Brain Imaging

Published on: June 21, 2017

10.0K

Related Experiment Videos

Last Updated: May 1, 2026

Three-dimensional Optical-resolution Photoacoustic Microscopy
08:31

Three-dimensional Optical-resolution Photoacoustic Microscopy

Published on: May 3, 2011

17.6K
Hand-held Clinical Photoacoustic Imaging System for Real-time Non-invasive Small Animal Imaging
09:43

Hand-held Clinical Photoacoustic Imaging System for Real-time Non-invasive Small Animal Imaging

Published on: October 16, 2017

10.4K
A High-performance Compact Photoacoustic Tomography System for In Vivo Small-animal Brain Imaging
05:32

A High-performance Compact Photoacoustic Tomography System for In Vivo Small-animal Brain Imaging

Published on: June 21, 2017

10.0K
  • Utilizing an intensity-modulated light source for PA signal excitation.
  • Testing the system with tissue phantoms to assess imaging performance.

    • Main Results:

    • Successful demonstration of the imaging capability of the frequency-domain PA system.
    • Observation of PA signals in tissue phantoms was achieved.
    • The system proved effective for hands-on PA signal detection training.

    Conclusions:

    • The developed frequency-domain PA system is a viable, low-cost alternative for biological tissue imaging.
    • The system serves as an excellent platform for educational purposes, facilitating practical learning in PA imaging.
    • Further exploration of PA effect mechanisms is supported by this accessible system.