Functional genomics down under: RNAi screening in the Victorian Centre for Functional Genomics

Area of Science:

• Genomics
• Cancer Research
• Molecular Biology

Background:

• The Peter MacCallum Cancer Centre is Australia's largest dedicated Cancer Research Institute.
• Functional genomics research is crucial for understanding cancer development and identifying new diagnostic tools.
• The Victorian Centre for Functional Genomics (VCFG) was established to provide access to cutting-edge technology.

Purpose of the Study:

• To document the technology platforms operated within the VCFG.
• To provide insight into the workflows and analysis pipelines at the VCFG.
• To highlight the VCFG's role in enabling functional genomics research across Australia and New Zealand.

Main Methods:

• Review of technology platforms.
• Description of operational workflows.
• Analysis of data processing pipelines.

Main Results:

• The VCFG houses advanced RNAi screening technology.
• Established workflows and analysis pipelines are in operation.
• The facility provides essential infrastructure and expertise.

Conclusions:

• The VCFG is a key resource for functional genomics research.
• It enables researchers to access cutting-edge technology and expertise.
• The facility supports cancer research advancements in Australia and New Zealand.