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Related Concept Videos

Fetal Circulation01:14

Fetal Circulation

5.0K
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
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Development of Blood Vessels01:07

Development of Blood Vessels

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The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
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Preconceptional family health evaluation: A regional education program for family planning clients and health professionals.

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Can changes in angiogenic biomarkers between the first and second trimesters of pregnancy predict development of pre-eclampsia in a low-risk nulliparous patient population?

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International guidelines for the diagnosis and management of hereditary haemorrhagic telangiectasia.

Journal of medical genetics·2009
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Prevention of alcohol-induced developmental delays and learning abnormalities in a model of fetal alcohol syndrome.

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Eucalyptol (1,8-cineole) relaxes umbilical veins in normoglycemic parturients and parturients with gestational diabetes mellitus by modulating ion channels: An ex vivo study.

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Transcriptomic profiling of human placental explants exposed to Plasmodium falciparum reveals activation of tissue-remodeling pathways and signatures associated with the Placenta-Brain Axis.

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Progesterone-KISS1 axis impairs amniotic epithelial cell function and promotes premature rupture of membranes.

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Author Spotlight: Advancing Research Through Single Cell Sequencing and Spatial Histology in Placental Tissues
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The Human Placenta Project: placental structure, development, and function in real time.

A E Guttmacher1, Y T Maddox1, C Y Spong1

  • 1Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, United States.

Placenta
|March 26, 2014
PubMed
Summary
This summary is machine-generated.

The placenta, vital for fetal and maternal health, remains poorly understood. This project aims to illuminate placental structure and function in real-time using advanced technologies.

Keywords:
Human placentaResearch

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Area of Science:

  • Reproductive Biology
  • Developmental Biology
  • Human Physiology

Background:

  • The placenta is critical for fetal and maternal health during pregnancy.
  • Limited understanding of placental structure and function poses risks to lifelong health for mother and child.
  • Growing evidence highlights placental development's impact on long-term health outcomes.

Purpose of the Study:

  • To propose a coordinated "Human Placenta Project".
  • To achieve a comprehensive understanding of human placental structure, development, and function.
  • To utilize modern technologies for real-time analysis of the placenta.

Main Methods:

  • Leveraging cutting-edge technologies and developing novel methodologies.
  • Implementing a coordinated, multi-faceted research approach.
  • Focusing on real-time observation and analysis.

Main Results:

  • N/A - This abstract proposes a project, not reporting results.
  • N/A
  • N/A

Conclusions:

  • A coordinated "Human Placenta Project" is essential.
  • Understanding placental function in real-time is achievable with current and developing technologies.
  • This project will advance knowledge critical for maternal and offspring health.