Association of dysfunctional uterine bleeding with high body mass index and obesity as a main predisposing factor

Dysfunctional uterine bleeding (DUB) defined as abnormal uterine bleeding in the absence of underlying structural abnormalities. Recently, obesity has been suggested as a main underling risk factor for DUB; however, evidences on the role of this predisposing factor are not adequate. The current study aimed to assess status of obesity in women who suffered from DUB.

In an observational case series study conducted at a referral endocrinology clinic in Shahrood city, Samnan, 20 consecutive women with the final diagnosis of DUB referred from 2009 to 2011 were evaluated. Obesity was assessed using calculation of body mass index (BMI) and waist circumference.

The mean waist circumference was estimated 102.95±9.77 cm in the range of 90-119 cm. With respect to BMI measurement, the mean of BMI was 32.63±3.34 kg/m(2) ranged between 26.92 and 39.06 that two-third of studied women suffered from overweight status and other one-third cases were obese.

There is a strong association between obesity and DUB and therefore weight reduction should be considered as a conservative treatment besides of other medical or surgical treatment approaches.