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Updated: May 1, 2026

Prospecting Microbial Strains for Bioremediation and Probiotics Development for Metaorganism Research and Preservation
Published on: October 31, 2019
Spirobisnaphthalenes from the mangrove-derived fungus Rhytidhysteron sp. AS21B
Khanitha Pudhom1, Thapong Teerawatananond2, Supichar Chookpaiboon3
1Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand. khanitha.p@chula.ac.th.
Abstract:
Three new spirobisnaphthalenes (1-3) were isolated from the mangrove-derived fungus Rhytidhysteron sp., together with five known derivatives (4-8). The structures of the compounds were established on the basis of extensive spectroscopic data, and the relative configurations of their stereogenic carbons were determined by a single-crystal X-ray crystallographic analysis. Compounds 3-5 displayed cytotoxicity against both cancer cell lines, MCF-7 and CaSki, while 2 was active only on CaSKi cells.
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