Related Experiment Video
Updated: May 1, 2026

A Simple Approach to Induce Experimental Autoimmune Neuritis in C57BL/6 Mice for Functional and Neuropathological Assessments
Published on: November 9, 2017
Mononeuritis multiplex: association with infectious condition and familial background in a tropical environment: a
Klaus Böck1, Carmen Pschaid, Raffi Topakian
1Department of Neurology, Wagner Jauregg Hospital, Wagner Jauregg Weg 15, 4021, Linz, Austria, klaus.boeck@gespag.at.
Abstract:
Mononeuritis multiplex is characterized by an asymmetric pattern with affection of the peripheral nervous system; this form of polyneuropathy is often seen in non-systemic vasculitis. We present a case of multiplex neuropathy in a patient with histologicaly verified Hailey-Hailey disease. With the exception of this comorbidity--in its characteristic form presenting additionally with a superinfected subdermal node--we did not find any other possible etiologic factor possibly causative of multiplex neuritis. The diagnosis was confirmed by electrophysiological testing. To our knowledge, this is the first case report indicating a possible relationship between Hailey-Hailey disease and multiplex neuritis. There exists only one related study in the literature, which was conducted in Columbia--our patient's home country. This study delineates a clinically similar dermal disease (pemphigus foliaceus) in patients from rural Colombia (El Bagre). The authors detected anti-neuronal antibodies which were interpreted to be responsible for the pathognomonic burning sensations.
Related Concept Videos
Encephalitis l: Introduction
Multiple Sclerosis l: Introduction
Encephalitis ll: Pathophysiology
Arboviral Encephalitis
Viral Meningitis
Fungal Phylum Microsporidia
