Related Experiment Video
Updated: May 1, 2026
09:56
In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
Published on: January 21, 2018
8.8K
Current and emerging therapies for ocular neovascularisation
Alison L Reynolds1, David Kent, Breandán N Kennedy
1School of Biomolecular and Biomedical Science, Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland, alison.reynolds@ucd.ie.
Advances in Experimental Medicine and Biology
|March 26, 2014
Summary
Ocular neovascularisation (ONV) treatments are reviewed, covering current options and emerging therapies. Future strategies focus on innovative drug delivery to the back of the eye for blinding diseases.
Area of Science:
- Ophthalmology
- Vascular Biology
- Pharmacology
Background:
- Ocular neovascularisation (ONV) is a key pathological process in numerous blinding eye diseases.
- Effective treatments are crucial to prevent vision loss associated with ONV.
Purpose of the Study:
- To review current pharmacological therapies for ONV.
- To highlight emerging therapies currently in clinical trials for ONV.
- To discuss future directions and desirable characteristics for novel ONV treatments.
Main Methods:
- Literature review of current and emerging pharmacological treatments for ocular neovascularisation.
- Analysis of clinical trial data for novel ONV therapies.
- Discussion of innovative drug delivery strategies for posterior segment eye diseases.
Main Results:
- Current therapies for ONV, while effective, have limitations.
- Several promising new therapies for ONV are advancing through clinical trials.
- Novel drug delivery systems are essential for improving treatment efficacy.
Conclusions:
- Ongoing research is vital for developing improved treatments for ONV.
- Future therapies should aim for enhanced efficacy and targeted delivery to the back of the eye.
- Innovative strategies are needed to combat blinding eye diseases caused by ONV.
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