Related Experiment Videos
Late renal failure due to prostatic outflow obstruction: a preventable disease
S H Sacks1, S A Aparicio, A Bevan
1Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Headington, Oxford.
BMJ (Clinical Research Ed.)
|January 21, 1989
Summary
Late renal failure from prostate issues is preventable. Early screening of kidney function in men with prostatism and better follow-up after prostatectomy can avert serious kidney damage.
Area of Science:
- Nephrology
- Urology
- Geriatric Medicine
Background:
- Prostatic outflow obstruction is a common cause of late-onset renal failure in older men.
- This condition, leading to end-stage renal disease, is often preventable with timely intervention.
Purpose of the Study:
- To retrospectively analyze case records of patients with late renal failure due to prostatic outflow obstruction.
- To identify potential areas for improved management and preventive strategies.
Main Methods:
- Retrospective analysis of 19 patients with renal failure secondary to prostatic enlargement.
- Review of patient records to assess referral times, treatment history, and renal function status.
Main Results:
- A significant delay (mean 2.8 years) was observed between the onset of prostatic symptoms and patient referral.
- Eight patients (47%) required long-term dialysis, with 80% needing initial dialysis support.
- Four patients who underwent prostatectomy were referred years later with recurrent symptoms and progressive nephropathy.
Conclusions:
- Progressive nephropathy due to prostatic outflow obstruction may be preventable.
- Enhanced screening of renal function in men with untreated prostatism is recommended.
- Closer follow-up for patients with uremia undergoing prostatectomy is crucial for preventing kidney damage.