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Acute pancreatitis in children: a tertiary hospital report

Henedina Antunes1, João Nascimento, Aurélio Mesquita

  • 1Gastroenterology, Hepatology and Nutrition Unit, Pediatrics Department, Hospital de Braga , Braga , Portugal.

Scandinavian Journal of Gastroenterology
|March 27, 2014
PubMed

Insights

Pediatric acute pancreatitis (AP) and acute recurrent pancreatitis (ARP) cases were reviewed. Etiologies included biliary stones and trauma, with specific lab values correlating to disease severity.

Area of Science:

  • Pediatric Gastroenterology
  • Hepatology
  • Pancreatology

Background:

  • The incidence of acute pancreatitis (AP) in children has risen significantly over the last two decades.
  • This study reviews pediatric pancreatitis cases from a Portuguese hospital.

Purpose of the Study:

  • To analyze the etiology, management, and outcomes of pediatric acute pancreatitis (AP) and acute recurrent pancreatitis (ARP).
  • To compare clinical and laboratory factors for disease severity assessment in children.

Main Methods:

  • Retrospective review of pediatric AP, ARP, and chronic pancreatitis cases (May 2002-May 2012).
  • Data analyzed included demographics, clinical, laboratory, and imaging findings.
  • Comparison of severity scores (pediatric acute pancreatitis severity score, CTSI) between mild and severe disease.

Main Results:

  • 37 patients (31 AP, 6 ARP) were identified.
  • Biliary stones/sludge (24.3%) and trauma (16.2%) were the most common causes.
  • Elevated white blood cell count, 48-h trough calcium, and 48-h rise in blood urea nitrogen correlated with severity.

Conclusions:

  • Pediatric pancreatitis has diverse and complex etiologies.
  • Improved pediatric-specific scoring systems and management protocols are necessary.
Abstract

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