Cardiac function and its evolution with pulmonary vasodilator therapy: a myocardial deformation study
Arvind Sehgal1, Masitah Ibrahim, Kenneth Tan
1Monash Newborn, Monash Children's Hospital, Melbourne, Australia; Department of Pediatrics, Monash University, Melbourne, Australia.
Speckle tracking echocardiography reveals impaired myocardial strain in infants with pulmonary hypertension. Inhaled nitric oxide therapy improved strain, highlighting its clinical utility for assessing cardiac function.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Echocardiography
Background:
- Speckle tracking echocardiography (STE) offers sensitive myocardial strain analysis.
- Conventional echocardiographic indices have limitations in assessing cardiac function.
Observation:
- A 3-month-old infant presented with pulmonary hypertension (PH) and impaired right ventricular function.
- Myocardial strain analysis revealed impaired and paradoxical segmental strain.
Findings:
- Inhaled nitric oxide therapy was initiated for the infant's PH.
- Post-treatment strain analysis demonstrated significant improvement in myocardial strain.
Implications:
- STE provides valuable insights into cardiac adaptation in infants with PH.
- Myocardial strain assessment aids in monitoring treatment response and guiding clinical management.
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